Characterisation of proteins by MS

Services
… range of technologies to fully characterise therapeutic proteins. Whether you are interested in monoclonal … antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality Assistance has the tools to support you for the characterisation of drug substances and drug products, QC …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Resources
… for each level of information you need (from intact protein to peptides/amino acids). Analytical performance of … is a very powerful technique widely used for the characterisation of biopharmaceuticals.  Thanks to … antibodies, based on three levels of analysis: Intact protein, mAb substructures (after IdeS / FabRICATOR …
Resources
… We presented efficient and optimised approaches for the characterisation of ADCs by mass spectrometry, based on different levels of analysis:  Intact protein for Drug-to-Antibody Ratio determination … you need.  … Mass Spectrometry Toolkit for the characterisation of ADCs … resource …
Resources
… Host-cell proteins are a major class of process-related impurities in … process development and for routine analyses. … … Characterisation of Anti-HCP antibodies by 2D differential …

SCIENTIST – High Resolution Mass Spectrometry

Jobs
… of analytical methods based on a protocol for the characterisation and quality control of (bio)molecules. … … knowledge and practical experience of analysis of peptides/proteins/mAbs by High Resolution Mass Spectrometry on Q-TOF … (U)HPLC and in HRMS on Q-TOF for the analysis of peptides/proteins/mAbs …

Glycosylation

Services
… Assistance analytical platform for the Physicochemical characterisation of Glycosylated Proteins … Glycosylation … service …

Peptide Mapping

Services
… … The method of choice for fine characterisation of proteins … Peptide Mapping … service …