Analysis of Oligonucleotides by Size-Exclusion Chromatography: SEC-UV, SEC-MS, SEC-MALS
The field of therapeutic oligonucleotides has seen remarkable progress over the last years.
The field of therapeutic oligonucleotides has seen remarkable progress over the last years.
ICP-MS/MS: An Innovative Approach for the Characterisation of Therapeutic Oligonucleotides
ICP-MS/MS methodologies were developed for the characterisation of therapeutic oligonucleotides:
Quality Assistance developed an innovative method for the absolute quantification of therapeutic oligonucleotides, as well as for the determination of phosphodiester-to-phosphorothioate (PO/PS) ratio by ICP-MS.MS.