KingFisher Flex purification system

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The KingFisher Flex is an automated system designed to process nucleic acids, proteins and cell samples efficiently. It delivers rapid and reproducible purification across a wide volume range using 24‑ or 96‑well formats. With predefined and customisable protocols, it supports high‑quality sample preparation for various laboratory workflows.

Advantages of the equipment

  • Automated and reproducible purification of DNA, RNA, proteins and cells
  • Handles volumes from 20 to 5000 μL depending on the plate format and magnetic head
  • Offers predefined and custom protocols via the BindIt software
  • Temperature control from 5°C above ambient to 115°C
  • Compatible with multiple magnetic heads (PCR, 96 deep‑well, 24 deep‑well)

Applications

The KingFisher Flex can be used to:

  • Quantify residual host cell DNA (CHO, E.coli, HEK…) or host cell proteins (CHO HCP or protein A) in pharmaceutical products
  • Detect mycoplasma contamination in biotherapeutics or culture supernatants
  • Digest proteins for HPLC and MS peptide mapping
  • Isolate specific cell populations (CD8+, CD4+ T‑cells, regulatory T‑cells, monocytes…) from PBMCs or directly from blood
  • Purify samples by immunoprecipitation prior to mass spectrometric analyses

Download our technical sheet to learn more about the equipment characteristics and principle

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