PEGylated Proteins
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… Protein PEGylation is a great tool to improve the delivery of therapeutic proteins, but it adds a level of complexity to the product. As well as the characterisation of individual components (PEG and protein), …
LAB SPECIALIST - Mass Spectrometry Protein Characterisation
Jobs
… to large molecules Very good knowledge of analysis of peptides/proteins/mAbs by High Resolution Mass Spectrometry … audits and investigations … Very good knowledge of peptides/proteins/mAbs analysis by High Resolution Mass …
Resources
… Absolute quantification of proteins ( i.e. quantification without the need for a … a very precise and very accurate absolute quantification of proteins. Compared to the reference method (amino acid … developed in our labs for the absolute quantification of proteins by ICP/MS. This method holds the potential to …
Absolute quantification of proteins by ICP/MS
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… sulfur determination. … Fast and accurate assay of single proteins by isotope dilution ICP/MS without the need of reference substance … Absolute quantification of proteins by ICP/MS … service …
Characterisation of proteins by MS
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… in monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Protein aggregation
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Resources
… Abstract Almost 60% of commercialized pharmaceutical proteins are glycosylated. Glycosylation is considered a … as it affects the stability, bioactivity and safety of proteins. Hence, the development of analytical methods to characterise the composition and structure of glycoproteins is crucial. Currently, existing methods are …