PEGylated Proteins

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Protein PEGylation is a great tool to improve the delivery of therapeutic proteins, but it adds a level of complexity to the product. As well as the characterisation of individual components (PEG and protein), …

Absolute quantification of proteins by ICP/MS

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… sulfur determination. … Fast and accurate assay of single proteins by isotope dilution ICP/MS without the need of reference substance … Absolute quantification of proteins by ICP/MS … service …

Characterisation of proteins by MS

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… range of technologies to fully characterise therapeutic proteins. Whether you are interested in monoclonal … antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality Assistance has the tools to support you for the characterisation of drug substances and drug products, QC …
Resources
… a state-of-the-art approach for absolute quantification of proteins , to be used for both biological reference standard … as a generic approach to be easily applied for different proteins or peptides even in matrices containing low … specific protein products. … … Absolute quantification of proteins by ICP-MS/MS … resource …
Resources
… Abstract Almost 60% of commercialized pharmaceutical proteins are glycosylated. Glycosylation is considered a … as it affects the stability, bioactivity and safety of proteins. Hence, the development of analytical methods to characterise the composition and structure of glycoproteins is crucial. Currently, existing methods are …