Characterisation of proteins by MS
Services
… in monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality …
LAB SPECIALIST - Mass Spectrometry Protein Characterisation
Jobs
… to large molecules Very good knowledge of analysis of peptides/proteins/mAbs by High Resolution Mass Spectrometry … audits and investigations … Very good knowledge of peptides/proteins/mAbs analysis by High Resolution Mass …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Resources
… and have developed a set of analytical workflows for the characterisation of biotherapeutics , with a strong focus … on: monoclonal antibodies antibody-drug conjugates fusion proteins These workflows can serve as generic methods in … sound expertise in Mass Spectrometry. … Mass Spectrometry protein characterisation at Quality Assistance … resource …
Resources
… A large number of pharmaceuti cals are glycosylated proteins. An adequate glycosylati on is criti cal for therapeuti c proteins in terms of safety, bioacti vity, solubility, … dynamics. … … State-of-the art LC/MS methods applied to the characterisation of a highly-glycosylated fusion protein: …
LAB R&D SCIENTIST – Characterisation of biomolecules
Jobs
… Very good technical expertise in (U)HPLC applied to peptides and proteins Very good practical knowledge of one … Very good knowledge of analysis and characterisation of peptides/proteins/mAbs, oligonucleotides, mRNA and/or viral … … Very good technical expertise in (U)HPLC applied to peptides and proteins. Very good practical knowledge of one …
PEGylated Proteins
Services
… Protein PEGylation is a great tool to improve the delivery of therapeutic proteins, but it adds a level of complexity to the product. As well as the characterisation of individual components (PEG and protein), …
Resources
… Host-cell proteins are a major class of process-related impurities in … test. This application note describes an approach for the characterisation of anti-HCP antibodies, and particularly … be used for routine testing of residual HCPs in therapeutic proteins is appropriate. Compared to traditional Western …