Characterisation of proteins by MS

Services
… range of technologies to fully characterise therapeutic proteins. Whether you are interested in monoclonal … antibodies (mAbs), antibody-drug conjugates (ADCs), fusion proteins, small or large proteins, Quality Assistance has the tools to support you for the characterisation of drug substances and drug products, QC …

R&D SPECIALIST – Protein characterisation

Jobs
… of analytical methods based on a protocol for the characterisation and quality control of (bio)molecules.   … … large molecules Very good knowledge of analysis of peptides/proteins/mAbs by High Resolution Mass Spectrometry on Q-TOF … our clients. … Very good knowledge of analysis of peptides/proteins/mAbs by High Resolution Mass Spectrometry on Q-TOF …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Resources
… A large number of pharmaceuti cals are glycosylated proteins. An adequate glycosylati on is criti cal for therapeuti c proteins in terms of safety, bioacti vity, solubility, … dynamics. … … State-of-the art LC/MS methods applied to the characterisation of a highly-glycosylated fusion protein: …
Resources
… and have developed a set of analytical workflows for the characterisation of biotherapeutics , with a strong focus … on: monoclonal antibodies antibody-drug conjugates fusion proteins These workflows can serve as generic methods in … sound expertise in Mass Spectrometry. … Mass Spectrometry protein characterisation at Quality Assistance … resource …
Resources
… separation (1D and 2D-LC), data processing / reporting for mAbs isoform characterisation (batch-to-batch consistency, … peptides/amino acids).  … 1D & 2D-LC/MS characterisation of mAbs for QC and stability testing … resource …

Oligonucleotides: A serious analytical challenge in terms of analytical characterisation

Article
… Oligonucleotides: A serious challenge in terms of analytical characterisation by Arnaud Delobel , R&D Director at Quality … a GMP/GLP environment. Though less complex than recombinant proteins, oligonucleotides represent a serious challenge in … available for the characterisation of peptide and protein drugs are constantly improving, less focus is put on …