Welcome to our scientific library!
Explore more of our expertise, R&D findings and analytical know-how by accessing this large portfolio of documents compiling both technical and regulatory information.
Study & Technical sheets
MALDI-TOF autoflex maXDownload the full document
Silicone-based impurities determination in biopharmaceuticalsDownload the full document
Organosilicon-based compounds such as PDMS (low-molecular weight polydimethylsiloxane, i.e., Dimeticone, Simeticone, Antifoam A®
Separation and biophysical characterisation of macromoleculesDownload the full document
Multi-Angle Light Scattering (MALS) detection allows for the determination of molecular weight distribution of biomolecules after size-exclusion chromatography (S
Multi-attribute monitoring of therapeutic mRNA by LC-MSDownload the poster
Interlaboratory evaluation of a user-friendly benchtop mass spectrometer for Multi-Attribute Monitoring studiesDownload the poster
Analysis of therapeutic mRNA by orthogonal separation methodsDownload the poster
A novel trypsin for accurate characterisation of biotherapeutic proteins with peptide mapping
ASMS Conference on Mass Spectrometry and Allied Topics
Publications & Application notes
Assessment of Squalene-Adenosine Nanoparticles in Two Rodent Models of Cardiac Ischemia-Reperfusion
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(1) Université Paris-Saclay, Institut Galien Paris-Saclay, CNRS UMR 8612, Pole Biologie-Pharmacie-Chimie, Bâtiment Henri Moissan, 6 Rue d’Arsonval, 91400 Orsay, France; email@example.com (R.B.)
Absolute quantification of proteins by ICP-MS/MS
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Since 2015, Quality Assistance proposes to its partners a method based on Sulphur specific ICP-MS/MS detection combined with an 34S/32S isotope dilution quantification.
The field of therapeutic oligonucleotides has seen remarkable progress over the last years. Oligonucleotides have emerged as promising
During this webinar, organised by Waters, Arnaud Delobel presents a method to demonstrate the effective implementation of Multiple Attribute
Webinar organised by Genovis
During this webinar entitled Multiple-Attribute Monitoring in QC: alternatives to the bottom-up approach
Host-cell proteins are a major class of process-related impurities in biotherapeutics that can impact the safety and efficacy of the product
BioLayer Interferometry (BLI) technology as an alternative to Surface Plasmon Resonance (SPR) in biopharma regulated environment
Live event organised by SelectScience
In this webinar recording, Arnaud Delobel presented the use of the BioLayer Interferometry (BLI)
Pyrogen testing is a regulatory requirement to ensure the product quality and safety of pharmaceutical products, as pyrogens can induce life
Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers. Unlike chemotherapy, ADCs are designed to
Webinar organised by Waters Corporation
In this webinar recording, we discussed the main challenges related to method development of size
Monoclonal antibodies (mAbs) constitute a major and fast-growing biotherapeutic class, thanks notably to their outstanding selectivity for
The production of monoclonal antibodies (mAbs) is a lengthy and complex process. It is, however, important to follow the mAb during
During this live webinar, we will outline the different analytical workflows that can be used for charge variant analysis (ion-exchange chromatography with salt or pH gradients, MS-compatible approaches, 2D-LC/MS, and icIEF) and present several case studies.
Access this 15 minutes webcast to learn more about an analytical method we have developed in our labs for the absolute quantification of proteins by ICP/MS.
Access this 15 minutes webcast to learn more about our large capacity and sound expertise in Mass Spectrometry.
Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard
Access this 45 minutes webinar to learn how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached with amino acid analysis.
Access this 20 minutes webcast to learn how Quality Assistance developed an ICP-MS/MS method based on the quantification of P and S after microwave digestion to determine the P=O/P=S ratio in oligonucleotide samples.
Access this 45 minutes webinar to learn how HDX-MS can be applied throughout the development of your product to get structural information that can hardly be obtained with other techniques. After a detailed description of the technique and its applications, case studies will be presented in the context of comparability and epitope mapping studies.
Access this 45 minutes webinar to learn how to characterise pluripotent stem cells in terms of identity and purity. The analytical performance of the methods developed have been discussed along with the presentation of experimental results obtained during method development, optimisation and/or validation.
Access this 45 minute webinar to learn how to characterise human mesenchymal stem cells in terms of identity, purity and biological activity. The analytical performance of the methods developed have been discussed along with the presentation of experimental results obtained during method development, optimisation and/or validation.
Join this 45 minute webinar to learn how to overcome the challenges usually associated to Multiplex assays and how to select the right technology for your needs.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each level of information you need.
Access this 45 minute webinar to learn how Surface Plasmon Resonance can be implemented in a GMP regulated environment for the comprehensive study of monoclonal antibodies and other Biologics.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of ADCs using analyses optimised for each level of information you need.
Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of monoclonal antibodies using analyses optimised for each level of information you need (from intact protein to peptides/amino acids).
Access this 30 minute webinar to learn how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Access this webinar which presented how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Although drug products issued from biotechnology have now been on the market for many years, accurate protein quantification remains a
Physico-chemical characterisation of rAAV
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During the conference "Challenges and Opportunities in Biotherapeutics Analytics", Damien Mouvet presented on the physico-chemical characterisation of rAAV. Download the slides to explore the topics and case studies he presented: