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… … Stress testing and physico-chemical characterisation of mAbs … resource …
2D-LC–MS for the Analysis of Monoclonal Antibodies and Antibody–Drug Conjugates in a Regulated Environment
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… the development and use for marketed monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs) of two-dimensional … environment. In recent years, monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs) have emerged as … companies in the development, release, and control of their mAbs and ADCs, in a regulated environment (such as the …
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… Due to their mode of production, therapeutic mAbs present diverse and heterogeneous glycosylations. Their … release and DMBlabelling, starting from small amounts of mAbs. The results are consistent with the N-glycosylation … what was found by released glycans analysis. Analysis of mAbs subunits, generated by IdeS enzyme digestion, followed …
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… Biologics and in particular monoclonal antibodies (mAbs) are an important class of therapeutics, and their market is growing. The production of mAbs is a complex and lengthy process. In-process …
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