TIDES Europe 2020


Quality Assistance attended TIDES Europe!

With more than 300 Oligonucleotide and Peptide Scientists and executives & 40+ case studies and new data presentations, TIDES Europe improves delivery and drive products to market through expert insight, new data and technology.

With more than 35 years’ experience, Quality Assistance has become a leader in analytical sciences and holds a unique position on the market with all its laboratories on one site and 200 highly qualified professionals.

Development and validation of analytical methods for:

Quality - CMC:

  • Characterisation

  • Stability studies

  • Batch testing

Safety & Efficacy - Bioanalysis:

  • PK

  • Immunogenicity

  • Biomarker studies

Oligonucleotide expertise

Due to their relatively large size as compared to typical small molecule drugs, there are many technical challenges associated with the analysis of oligonucleotides. With a highly experienced staff and state-of-the-art premises and equipment, Quality Assistance is your partner of choice to overcome your analytical hurdles and facilitate the registration process.

customer support oligonucleotide

OLIGONUCLEOTIDES: absolute quantification and P=O/P=S ratio in a single ICP-MS/MS run

Phosphodiester to phosphorothioate ratio (P=O/P=S) is a critical quality attribute of phosphorothioate oligonucleotides. Quality Assistance developed an ICP-MS/MS method based on the quantification of P and S after microwave digestion to determine the P=O/P=S ratio in oligonucleotide samples. This method offers excellent precision and accuracy on reference standards and therapeutic oligonucleotide samples and can be used in routine testing in a GxP environment, as an orthogonal method to 31P-NMR.

Simultaneous determination of Phosphorus and Sulfur by ICP-MS/MS allowing for:

  • an accurate quantification of oligonucleotides, without reference substance
  • an easy determination of the P=O/P=S ratio for phosphorothioates

Watch this 20-minute-webcast to learn more

Download the slides now


slides oligonucleotides webinar quality assistance

Peptide expertise

Therapeutic peptides are at the crossroads of small molecules and proteins, requiring specific analytical packages depending on whether they are of recombinant or synthetic origin. Quality Assistance provides customised solutions in terms of analytical protocols and innovative technologies to help you move your peptide through non-clinical and clinical development towards registration.

customer support peptide


More info:

TIDES Europe website

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