State-of-the art LC/MS methods applied to the characterisation of a highly-glycosylated fusion protein: Etanercept

Eric Largy
Fabrice Cantais
Arnaud Delobel
Analytical Technologies Europe 2017

A large number of pharmaceuti cals are glycosylated proteins. An adequate glycosylati on is criti cal for therapeuti c proteins in terms of safety, bioacti vity, solubility, stability, and pharmacokinetics and dynamics.