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Addressing common challenges of biotherapeutic protein peptide mapping using recombinant trypsin

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… proteins. This method relies on digestion of proteins into peptides that are then analyzed for amino acid sequence and … cleavage activity causing generation of semi-tryptic peptides and degradation of trypticspecific peptides. Furthermore, MS-grade trypsins contained …

Fast and accurate absolute quantification of proteins and antibodies by ICP-MS

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… (...) … … Fast and accurate absolute quantification of proteins and antibodies by ICP-MS … resource …

State-of-the art LC/MS methods applied to the characterisation of a highly-glycosylated fusion protein: Etanercept

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… A large number of pharmaceuti cals are glycosylated proteins. An adequate glycosylati on is criti cal for therapeuti c proteins in terms of safety, bioacti vity, solubility, …

New developments in the absolute quantification of proteins

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… Absolute quantification of proteins ( i.e. quantification without the need for a … a very precise and very accurate absolute quantification of proteins. Compared to the reference method (amino acid … … New developments in the absolute quantification of proteins … article …

How to manage the dilution effect observed in the quantification of residual CHO host cell proteins using commercialized ELISA kits?

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… of the purification procedure to remove unwanted host cell proteins (HCPs) should be investigated thoroughly, as should … observed in the quantification of residual CHO host cell proteins using commercialized ELISA kits? … resource …

Fast and accurate absolute-quantification of proteins and antibodies using Isotope Dilution-Triple Quadrupole ICP-MS

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… Fast and accurate absolute-quantification of proteins and antibodies using Isotope Dilution-Triple … systems. … Fast and accurate absolute-quantification of proteins and antibodies using Isotope Dilution-Triple …

Mass Spectrometry protein characterisation at Quality Assistance

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… on: monoclonal antibodies antibody-drug conjugates fusion proteins These workflows can serve as generic methods in …

Absolute quantification of proteins & mAbs by ICP-MS

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… cati on remains a challenge. … … Absolute quantification of proteins & mAbs by ICP-MS … resource …

WEBINAR Méthodes génériques pour l’analyse de protéines en SEC

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Therapeutic Protein Charge Variants Characterisation using icIEF fractionation and MS

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