Multiple Attribute Monitoring of therapeutic mRNA

Thomas Menneteau
Waters Biopharma Seminar Day

During Waters Biopharma Seminar Day, Thomas Menneteau, R&D Scientist, presented on the Multiple Attribute Monitoring of therapeutic mRNA. During his presentation, he covered the following topic:

  • How mRNA therapeutics work?
  • Regulatory requirements and analytical procedures for mRNA vaccine quality
  • Determination of 5’ cap identity and percentage
  • Determination of polyA tail length distribution
  • 2 case studies: analysis of a drug substance and a drug product

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