NLS Days 2022
Events
… an expert for the development of NBEs  ( mAbs ,  ADCs ,  proteins ) NCEs ,  oligonucleotides ,  peptides mRNA … Validation of analytical methods as per ICH guidelines Characterisation of ADCs at intact, sub-unit and peptide …

MALDI-TOF autoflex maX
Services
… following applications:   Molecular weight determination (mAbs, ADCs, oligonucleotides, peptides, vaccines) N and O-glycan profiling and peptide mapping (mAbs) Analysis of heterogeneous compounds (e.g. PEGylated …

Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Resources
… a powerful tool for the characterisation of two commercial ADCs, brentuximab vedotin (Adcetris ® ) and trastuzumab … set of methods has been developed to characterise ADCs at the intact, subunit, and peptide level. These … applicable to either or both lysine- and cysteineconjugated ADCs. Herein, determination of the drug load distribution …