PEGylated Proteins
Services
… Protein PEGylation is a great tool to improve the delivery of therapeutic proteins, but it adds a level of complexity to the product. As well as the characterisation of individual components (PEG and protein), …
Resources
… Absolute quantification of proteins ( i.e. quantification without the need for a … a very precise and very accurate absolute quantification of proteins. Compared to the reference method (amino acid … developed in our labs for the absolute quantification of proteins by ICP/MS. This method holds the potential to …
Absolute quantification of proteins by ICP/MS
Services
… other hand, the LC-MS/MS determination of specific tryptic peptides lacks reproducibility due to the variability of the …
Resources
… can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each … We presented efficient and optimized approaches for the characterisation of protein glycosylation by UPLC/mass spectrometry, based on …
Protein aggregation
Services
… Protein aggregation is a major concern for biotherapeutics … there is still no specific guidance on biopharmaceutical protein aggregates, regulatory agencies have clearly highlighted the need for the in-depth characterisation and monitoring of aggregation. Quality …
Our webinar is online: Mass spectrometry toolkit for the characterisation of protein glycosylation
Article
… Assistance webinar Mass spectrometry toolkit for the characterisation of protein glycosylation given on July 12th at 16.00 … Due to their mode of production, therapeutic glycoproteins present complex and heterogeneous glycosylations. …
Resources
… a state-of-the-art approach for absolute quantification of proteins , to be used for both biological reference standard … as a generic approach to be easily applied for different proteins or peptides even in matrices containing low … specific protein products. … … Absolute quantification of proteins by ICP-MS/MS … resource …
Resources
… Abstract Almost 60% of commercialized pharmaceutical proteins are glycosylated. Glycosylation is considered a … as it affects the stability, bioactivity and safety of proteins. Hence, the development of analytical methods to characterise the composition and structure of glycoproteins is crucial. Currently, existing methods are …
Advanced Analytical Technologies for Proteins 2019
Events
… Assistance attended Advanced Analytical Technologies for Proteins conference Quality Assistance is the one-stop shop … trust our excellence and know-how in analysing their proteins . From discovery to the marketplace, Quality … Arnaud Delobel, R&D Director, presented on the structural characterisation and epitope mapping by HDX-MS. Contact us …