Scientific Library: results

Conference

Quality Assistance Oligonucleotide

Oligonucleotides : absolute quantification and P=O/P=S ratio in a single ICP-MS/MS run

ICP-MS can be a solution for a fast and accurate generic method for oligonucleotides quantification without the reference oligo !

Authors
Philippe De Raeve, Scientific Director
Orthogonal LC/MS methods characterisation therapeutic glycoproteins Arnaud Delobel Quality Assistance

Orthogonal LC/MS methods for the comprehensive characterisation of therapeutic glycoproteins

Glycosylation is critical for the safety and efficacy of biotherapeutics.

Authors
Arnaud Delobel

Publication & Application note

Development, optimisation and validation of a TNFα neutralising assay using a Quality by Design approach

Authors
Fabian Vandermeers
Capucine Lepers
Florence Dusserre-Bresson
Christelle Plennevaux
Stéphanie Pennincx
Julie Nicaise
Estelle Lara
Vincent Bertholet
Arnaud Delobel

Innovative ICP-MS/MS approach for the determination of phosphodiester to phosphorothioate ratio in phosphorothioate oligonucleotides

Authors
Juliusz Bianga
Caroline Cajot
Philippe De Raeve
Arnaud Delobel

Stress testing of Humira (adalimumab) monitored by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Arnaud Delobel

Epitope mapping of an interleukin receptor for three therapeutic antibodies by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Caroline Cajot
Arnaud Delobel

Analytical Characterisation of Cell-Based Medicinal Products

Authors
Fabian Vandermeers
Sandra Thys
Valérie Deffontaine
Estelle Lara
Arnaud Delobel

Analytical approaches for the evaluation of ADCC activity of mAbs

Authors
Arnaud Delobel
Florence Dusserre-Bresson
Eric Largy
Capucine Lepers
Cléa Mantini
Christelle Plennevaux
Fabian Vandermeers

Customised labelling of antibodies: A powerful tool for multi-parameters analyses in Flow Cytometry

Authors
Valérie Deffontaine
Fabian Vandermeers
Capucine Lepers
Géry Van Vyncht
Arnaud Delobel

Scientific poster

Oligonucleotides: Absolute quantification and P=O/P=S in a single ICP-MS/MS run

Authors
Juliusz Bianga
Philippe De Raeve
Arnaud Delobel
Caroline Cajot
Location
TIDES 2018

Epitope mapping of an interleukin receptor for three therapeutic antibodies by HDX-MS

Authors
Eric Largy
Caroline Cajot
Arnaud Delobel
Location
Analytical Technologies Europe 2018

Bioanalysis of 9 elemental impurities in human whole blood and urine samples by ICP-MS

Authors
Olivier Lurkin
Albin Jouran
Marie-Odile Galcera
Stéphane Frécinaux
Location
EBF Open Symposium 2017

Mass Spectrometry as a tool for the Bioanalysis of Antibody-Drug Conjugates (ADCs)

Authors
Stéphane Frécinaux
Arnaud Delobel
Location
EBF Open Symposium 2017

Development and optimization of a TNFα neutralizing assay using a Quality by Design approach

Authors
Fabian Vandermeers
Capucine Lepers
Florence Dusserre-Bresson
Christelle Plennevaux
Stéphanie Pennincx
Julie Nicaise
Estelle Lara
Arnaud Delobel
Location
BEBPA 2017

Absolute quantification of proteins & mAbs by ICP-MS

Authors
Julius Bianga
Philippe De Raeve
Arnaud Delobel
Location
Analytical Technologies Europe 2017

State-of-the art LC/MS methods applied to the characterisati on of a highly-glycosylated fusion protein: Etanercept

Authors
Eric Largy
Fabrice Cantais
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Multi-level mass spectrometric characterisation of Antibody-Drug Conjugates in a regulated environment

Authors
Eric Largy
Anicet Catrain
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Webinar

Characterisation of human pluripotent stem cells (ESC and IPSC) and by-products

The discovery of human pluripotent stem cells 10 years ago turned the spotlight on the potential of pluripotent stem cells for personalised cell therapy. The scientific interest then quickly shifted towards the use of these cells for safety pharmacology, drug discovery and disease modelling.

Authors
Valérie Deffontaine, R&D Scientist

The challenge of human mesenchymal stem cells (MSCs) characterisation

Access this 45 minute webinar to learn how to characterise human mesenchymal stem cells in terms of identity, purity and biological activity.

Authors
Sandra Thys, R&D Scientist

Cytokine Release: Comparison of Multiplex and Simplex assays

Access this 45 minute webinar to learn:

Authors
Quality Assistance