Publications & Application notes

Fast and accurate absolute quantification of antibodies and antibody-drug conjugate using Isotope Dilution-Triple Quadrupole ICP-MS

Authors
Juliusz Bianga
Philippe De Raeve
Magali Perez
Arnaud Delobel
Download the poster

Analytical approaches for the evaluation of ADCC activity of mAbs

Authors
Arnaud Delobel
Florence Dusserre-Bresson
Eric Largy
Capucine Lepers
Cléa Mantini
Christelle Plennevaux
Fabian Vandermeers
Download the poster

Customised labelling of antibodies: A powerful tool for multi-parameters analyses in Flow Cytometry

Authors
Valérie Deffontaine
Fabian Vandermeers
Capucine Lepers
Géry Van Vyncht
Arnaud Delobel
Download the poster

Characterisation of the glycosylation of Humira (adalimumab) and Erbitux (Cetuximab) by high resolution mass spectrometry

Authors
Eric Largy
Fabrice Cantais
Géry Van Vyncht
Arnaud Delobel
Download the poster

Characterisation of Anti-HCP antibodies by 2D differential Gel Electrophoreses

Authors
Arnaud Delobel
Alix Verret
Nicolas Trinchero
Géry Van Vyncht
Download the poster

Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Anicet Catrain,
Géry Van Vyncht
Download the poster

Webinar

Absolute quantification of proteins: forget amino acid analysis and shift to the new gold standard

Access this 15 minutes webcast to learn more about an analytical method we have developed in our labs for the absolute quantification of proteins by ICP/MS.
Authors
Dr. Arnaud Delobel
Download the slides

Mass Spectrometry protein characterisation at Quality Assistance

Access this 15 minutes webcast to learn more about our large capacity and sound expertise in Mass Spectrometry.
Authors
Dr. Arnaud Delobel
Download the slides

Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard

Access this 45 minutes webinar to learn how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached with amino acid analysis.
Authors
Dr Arnaud Delobel
Download the slides

HDX-MS a powerful tool for biopharmaceutical characterisation

Access this 45 minutes webinar to learn how HDX-MS can be applied throughout the development of your product to get structural information that can hardly be obtained with other techniques. After a detailed description of the technique and its applications, case studies will be presented in the context of comparability and epitope mapping studies.
Authors
Dr Arnaud Delobel
Download the slides

Cytokine Release: Comparison of Multiplex and Simplex assays

Join this 45 minute webinar to learn how to overcome the challenges usually associated to Multiplex assays and how to select the right technology for your needs.
Authors
Quality Assistance
Download the slides

Conference

Quality Assistance waters dublin webaf

Multiple Heartcut 2D-LC/MS: a powerful tool for biopharma analysis in a regulated environment

Multiple Heartcut 2D-LC/MS is a powerful tool for biopharma analysis in a regulated environment.
Authors
Dr Arnaud Delobel, R&D Director
Download the slides
Adebiotech AATP Proteins Delobel Quality Assistance

Structural characterisation and epitope mapping by HDX-MS

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) is an innovative tool for the characterisation of biotherapeutics.
Authors
Dr Arnaud Delobel
Download the slides
Quality Assistance glycosylation proteins

Orthogonal LC/MS methods for the comprehensive characterisation of therapeutic glycoproteins

Glycosylation is critical for the safety and efficacy of biotherapeutics.
Authors
Dr Arnaud Delobel, R&D Director
Download the slides
quality assistance ICP scientist

Absolute quantification of mAbs and ADCs : forget amino acid analysis and shift to the new gold standard

Absolute quantification of mAbs and ADCs: Quality Assistance developed an innovative analytical method based on sulfur quantification by ICP-MS/MS
Authors
Dr Arnaud Delobel, R&D Director
Download the slides
Nouveaux outils pour la caractérisation et l'analyse structurale des mAbs et ADCs Quality Assistance Arnaud Delobel

Nouveaux outils pour la caractérisation et l'analyse structurale des mAbs et ADCs

La spectrométrie de masse est un outil indispensable pour la caractérisation des protéines thérapeutiques.
Authors
Dr Arnaud Delobel, R&D Director
Download the slides

Scientific poster

Mass Spectrometry as a tool for the Bioanalysis of Antibody-Drug Conjugates (ADCs)

Authors
Stéphane Frécinaux
Arnaud Delobel
Location
EBF Open Symposium 2017
Download the poster

Development and optimization of a TNFα neutralizing assay using a Quality by Design approach

Authors
Fabian Vandermeers
Capucine Lepers
Florence Dusserre-Bresson
Christelle Plennevaux
Stéphanie Pennincx
Julie Nicaise
Estelle Lara
Arnaud Delobel
Location
BEBPA 2017
Download the poster

Absolute quantification of proteins & mAbs by ICP-MS

Authors
Julius Bianga
Philippe De Raeve
Arnaud Delobel
Location
Analytical Technologies Europe 2017
Download the poster

Multi-level mass spectrometric characterisation of Antibody-Drug Conjugates in a regulated environment

Authors
Eric Largy
Anicet Catrain
Arnaud Delobel
Location
Analytical Technologies Europe 2017
Download the poster

Scientific Library: results