Scientific Library: results

Webinar

Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard

Absolute quantification of proteins (i.e. quantification without the need for a reference standard) is a key analysis for the qualification of reference standards or to determine the extinction coefficient of a protein. It is usually performed using amino acid an

Authors
Dr Arnaud Delobel

HDX-MS a powerful tool for biopharmaceutical characterisation

Access this 45 minutes webinar to learn how HDX-MS can be applied throughout the development of your product to get structural information that can hardly be obtained with other techniques.

Authors
Dr Arnaud Delobel

Cytokine Release: Comparison of Multiplex and Simplex assays

Access this 45 minute webinar to learn:

Authors
Quality Assistance

Mass Spectrometry Toolkit for the characterisation of ADCs

Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of ADCs using analyses optimised for each level of information you need. 

Authors
Arnaud Delobel, Scientific Manager

Excipient & API suppliers: ICH Q3D is also for you!

Access this 30 minute webinar to learn how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products. 

Authors
Philippe De Raeve, Scientific Director

Conference

Quality Assistance glycosylation proteins

Orthogonal LC/MS methods for the comprehensive characterisation of therapeutic glycoproteins

Glycosylation is critical for the safety and efficacy of biotherapeutics.

Authors
Dr Arnaud Delobel, R&D Director
quality assistance ICP scientist

Absolute quantification of mAbs and ADCs : forget amino acid analysis and shift to the new gold standard

Absolute quantification of mAbs and ADCs: Quality Assistance developed an innovative analytical method based on sulfur quantification by ICP-MS/MS
 

Authors
Dr Arnaud Delobel, R&D Director
Nouveaux outils pour la caractérisation et l'analyse structurale des mAbs et ADCs Quality Assistance Arnaud Delobel

Nouveaux outils pour la caractérisation et l'analyse structurale des mAbs et ADCs

La spectrométrie de masse est un outil indispensable pour la caractérisation des protéines thérapeutiques.

Authors
Dr Arnaud Delobel, R&D Director

Scientific poster

Mass Spectrometry as a tool for the Bioanalysis of Antibody-Drug Conjugates (ADCs)

Authors
Stéphane Frécinaux
Arnaud Delobel
Location
EBF Open Symposium 2017

Development and optimization of a TNFα neutralizing assay using a Quality by Design approach

Authors
Fabian Vandermeers
Capucine Lepers
Florence Dusserre-Bresson
Christelle Plennevaux
Stéphanie Pennincx
Julie Nicaise
Estelle Lara
Arnaud Delobel
Location
BEBPA 2017

Absolute quantification of proteins & mAbs by ICP-MS

Authors
Julius Bianga
Philippe De Raeve
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Multi-level mass spectrometric characterisation of Antibody-Drug Conjugates in a regulated environment

Authors
Eric Largy
Anicet Catrain
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Development and use of 2D-LC/MS as a versatile and powerful tool for the analysis of mAbs and ADCs in a regulated environment

Authors
Eric Largy
Anicet Catrain
Géry Van Vyncht
Arnaud Delobel
Location
Analytical Technologies Europe 2016

Publication & Application note

Analytical approaches for the evaluation of ADCC activity of mAbs

Authors
Arnaud Delobel
Florence Dusserre-Bresson
Eric Largy
Capucine Lepers
Cléa Mantini
Christelle Plennevaux
Fabian Vandermeers

Customised labelling of antibodies: A powerful tool for multi-parameters analyses in Flow Cytometry

Authors
Valérie Deffontaine
Fabian Vandermeers
Capucine Lepers
Géry Van Vyncht
Arnaud Delobel

Characterisation of the glycosylation of Humira (adalimumab) and Erbitux (Cetuximab) by high resolution mass spectrometry

Authors
Eric Largy
Fabrice Cantais
Géry Van Vyncht
Arnaud Delobel

Characterisation of Anti-HCP antibodies by 2D differential Gel Electrophoreses

Authors
Arnaud Delobel
Alix Verret
Nicolas Trinchero
Géry Van Vyncht

Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Anicet Catrain,
Géry Van Vyncht

Surface Plasmon Resonance

Authors
Arnaud Delobel
Fabian Vandermeers
Valérie Deffontaine

Characterisation of Humira Adalimumab by high resolution mass spectrometry

Authors
Fabrice Cantais
Anicet Catrain
Eric Largy
Géry Van Vyncht
Arnaud Delobel