Peptide Mapping
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… method of choice for the characterisation of therapeutic proteins, and is one of the analytical techniques required … … The method of choice for fine characterisation of proteins … Peptide Mapping … service …
Product characterisation by High-Resolution Mass Spectrometry (HRMS)
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… Mass Spectrometry (HRMS) solutions to support the characterisation of a wide range of therapeutic modalities. … range of technologies to fully characterise therapeutic proteins. … Product characterisation by High-Resolution Mass Spectrometry (HRMS) …
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… analysis (ID-ICP-QQQ) of sulphur, for the quantification of proteins, including antibodies and ADCs. The method , which …
KingFisher Flex
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… is a device that automatically processes nucleic acids, proteins or cell samples . The system offers rapid and reproducible purification of high-quality DNA, RNA, proteins and cells for various types of applications. … residual host cell DNA (CHO, E.coli, HEK,…) or host cell proteins (CHO HCP or protein A) in pharmaceutical products. …
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… Host-cell proteins are a major class of process-related impurities in … be used for routine testing of residual HCPs in therapeutic proteins is appropriate. Compared to traditional Western … Blot approaches with visual comparisons of the gels (total proteins vs. proteins detected by the antibodies), the …
WEBINAR: Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard
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… to the new gold standard Absolute quantification of proteins ( i.e. quantification without the need for a … be obtained, which provides a reliable quantification of proteins and determination of extinction coefficients. … how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached …
Always at the forefront of analytical sciences
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… our capacity for the automatic process of nucleic acids, proteins or cell samples . The KingFisher Flex system offers … and reproducible purification of high-quality DNA, RNA, proteins and cells for various types of applications : Quantification of residual host cell DNA or host cell proteins Detection of mycoplasma contamination Digestion of …
2D UPLC/MS
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Mass spectrometry as a powerful tool for the characterisation of monoclonal antibodies in the context of comparability studies
Article
… glycoengineering of therapeutic antibodies and Fc-fusion proteins. Curr. Pharm. Biotechnol. 9, 482–501 (2008) … In …