Oligonucleotides: A serious analytical challenge in terms of analytical characterisation
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… a GMP/GLP environment. Though less complex than recombinant proteins, oligonucleotides represent a serious challenge in …
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… molecules are designed to allow cells to produce critical proteins and enzymes that can help fight disease. The …
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2D-LC–MS for the Analysis of Monoclonal Antibodies and Antibody–Drug Conjugates in a Regulated Environment
Article
… LC–MS Antibody–drug conjugates are therapeutic proteins that combine the selectivity of mAbs and the …
State-of-the-Art MS Methods for Structural Assessment of mAbs and ADCs: From the Research Lab to Routine Characterization
Article
… antibodies (mAbs) are highly complex tetrameric glycoproteins that require extensive analytical and structural … with MS detection is widely used for the identification of proteins from complex proteome samples in many laboratories. …