Scientific Library: results

Conference

quality assistance ICP scientist

Absolute quantification of mAbs and ADCs : forget amino acid analysis and shift to the new gold standard

Absolute quantification of mAbs and ADCs: Quality Assistance developed an innovative analytical method based on sulfur quantification by ICP-MS/MS
 

Authors
Dr Arnaud Delobel, R&D Director

Q3D - Elemental Impurities

What implications for APIs & excipients suppliers?

15th Oct 2015
Authors
Philippe De Raeve, Scientific Director

Publication & Application note

Stress testing of Humira (adalimumab) monitored by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Arnaud Delobel

Epitope mapping of an interleukin receptor for three therapeutic antibodies by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Caroline Cajot
Arnaud Delobel

Customised labelling of antibodies: A powerful tool for multi-parameters analyses in Flow Cytometry

Authors
Valérie Deffontaine
Fabian Vandermeers
Capucine Lepers
Géry Van Vyncht
Arnaud Delobel

Characterisation of the glycosylation of Humira (adalimumab) and Erbitux (Cetuximab) by high resolution mass spectrometry

Authors
Eric Largy
Fabrice Cantais
Géry Van Vyncht
Arnaud Delobel

Characterisation of Anti-HCP antibodies by 2D differential Gel Electrophoreses

Authors
Arnaud Delobel
Alix Verret
Nicolas Trinchero
Géry Van Vyncht

Characterisation of the glycosylation of Enbrel: Etanercept by high resolution mass spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Géry Van Vyncht

Surface Plasmon Resonance

Authors
Arnaud Delobel
Fabian Vandermeers
Valérie Deffontaine

Characterisation of Humira Adalimumab by high resolution mass spectrometry

Authors
Fabrice Cantais
Anicet Catrain
Eric Largy
Géry Van Vyncht
Arnaud Delobel

Fast and accurate absolute-quantification of proteins and antibodies using Isotope Dilution-Triple Quadrupole ICP-MS

Authors
Agilent Technologies
Philippe De Raeve
Juliusz Bianga

Scientific poster

Development and optimization of a TNFα neutralizing assay using a Quality by Design approach

Authors
Fabian Vandermeers
Capucine Lepers
Florence Dusserre-Bresson
Christelle Plennevaux
Stéphanie Pennincx
Julie Nicaise
Estelle Lara
Arnaud Delobel
Location
BEBPA 2017

Absolute quantification of proteins & mAbs by ICP-MS

Authors
Julius Bianga
Philippe De Raeve
Arnaud Delobel
Location
Analytical Technologies Europe 2017

State-of-the art LC/MS methods applied to the characterisati on of a highly-glycosylated fusion protein: Etanercept

Authors
Eric Largy
Fabrice Cantais
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Development and use of 2D-LC/MS as a versatile and powerful tool for the analysis of mAbs and ADCs in a regulated environment

Authors
Eric Largy
Anicet Catrain
Géry Van Vyncht
Arnaud Delobel
Location
Analytical Technologies Europe 2016

Characterizing Deamidation and Oxidation in Adalimumab with Low pH Peptide Mapping and Middle-Up Mass Spec Analysis.

Authors
Chris Hosfield
Eric Largy
Anicet Catrain
Fabrice Cantais
Géry Van Vyncht
Michael Rosenblatt
Sergei Saveliev
Marjeta Urh
Arnaud Delobel
Location
ASMS Sanibel Conference 2016

Elemental impurities: how to be compliant with ICH Q3D guideline?

Authors
Philippe De Raeve
Pascal Brichart
Julius Bianga
Géry Van Vyncht
Arnaud Delobel
Location
CPhI ISCE 2015

Webinar

Cytokine Release: Comparison of Multiplex and Simplex assays

Access this 45 minute webinar to learn:

Authors
Quality Assistance

Mass spectrometry toolkit for the characterisation of protein glycosylation

Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each level of information you need. 

Authors
Quality Assistance

Excipient & API suppliers: ICH Q3D is also for you!

Access this 30 minute webinar to learn how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products. 

Authors
Philippe De Raeve, Scientific Director