Fast and accurate absolute-quantification by ICP-MS

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… a fast and accurate method for absolute-quantification of proteins and antibodies using Isotope Dilution -Triple … with them.  Fast and accurate absolute-quantification of proteins and antibodies  using Isotope Dilution-Triple … of many elements, enabling quantification of metalloproteins and peptides through the use of isotope dilution …
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… Host-cell proteins are a major class of process-related impurities in … be used for routine testing of residual HCPs in therapeutic proteins is appropriate. Compared to traditional Western … Blot approaches with visual comparisons of the gels (total proteins vs. proteins detected by the antibodies), the …

Glycosylation

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… Recombinant proteins are increasingly used as therapeutics, and they … Adequate glycosylation is critical for therapeutic proteins regarding binding, solubility and stability, … Consequently, the glycosylation profile of therapeutic proteins is considered a critical quality attribute and it …