Development and validation of an antibody-drug conjugate bioassay

Resources
… Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers.  Unlike chemotherapy, ADCs are  designed to only target and kill tumour cells.  Structurally, ADCs are complex molecules composed of an antibody linked to …

Development and validation of an antibody-drug conjugate bioassay

Resources
… Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers. Unlike chemotherapy, ADCs are designed to only target and kill tumour cells. Structurally, ADCs are complex molecules composed of an antibody linked to …

Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Resources
… a powerful tool for the characterisation of two commercial ADCs, brentuximab vedotin (Adcetris ® ) and trastuzumab … set of methods has been developed to characterise ADCs at the intact, subunit, and peptide level. These … applicable to either or both lysine- and cysteineconjugated ADCs. Herein, determination of the drug load distribution …

German Biotech Days 2024
Events
… services Elemental impurities Characterisation of proteins by MS ABOUT THE EVENT Visit …