Scientific Library: results

Scientific poster

Development of orthogonal chromatographic methods for the purity analysis of therapeutic oligonucleotides

Authors
Morgane Lescut
Claire Butré
Arnaud Delobel
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Oligonucleotides: Absolute quantification and P=O/P=S in a single ICP-MS/MS run

Authors
Juliusz Bianga
Philippe De Raeve
Arnaud Delobel
Caroline Cajot
Location
TIDES 2018
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Elemental impurities: how to be compliant with ICH Q3D guideline?

Authors
Philippe De Raeve
Pascal Brichart
Julius Bianga
Géry Van Vyncht
Arnaud Delobel
Location
CPhI ISCE 2015
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Publications & Application notes

Development of orthogonal chromatographic methods for the purity analysis of therapeutic oligonucleotides

Authors
Arnaud Delobel
Claire Butré
Morgane Lescut
Download the poster

Absolute Quantification of Oligonucleotides by ICP-MS/MS

Authors
Arnaud Delobel
Juliusz Bianga
Magali Perez
Damien Mouvet
Caroline Cajot
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Innovative ICP-MS/MS approach for the determination of phosphodiester to phosphorothioate ratio in phosphorothioate oligonucleotides

Authors
Juliusz Bianga
Caroline Cajot
Philippe De Raeve
Arnaud Delobel
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Webinar

OLIGONUCLEOTIDES: absolute quantification and P=O/P=S ratio in a single ICP-MS/MS run

Access this 20 minutes webcast to learn how Quality Assistance developed an ICP-MS/MS method based on the quantification of P and S after microwave digestion to determine the P=O/P=S ratio in oligonucleotide samples.
Authors
Philippe De Raeve
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Excipient & API suppliers: ICH Q3D is also for you!

Access this 30 minute webinar to learn how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Authors
Philippe De Raeve, Scientific Director
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Elemental Impurities: How to be compliant with Q3D ?

Access this webinar which presented how the Q3D guideline for EIs can be efficiently implemented for all drug substances, excipients and drug products.
Authors
Philippe De Raeve, Scientific Director
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Conference

Quality Assistance Oligonucleotide

Oligonucleotides : absolute quantification and P=O/P=S ratio in a single ICP-MS/MS run

ICP-MS can be a solution for a fast and accurate generic method for oligonucleotides quantification without the reference oligo !
Authors
Philippe De Raeve, Scientific Director
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Q3D - Elemental Impurities

What implications for APIs & excipients suppliers?
Authors
Philippe De Raeve, Scientific Director
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