Nowadays, biopharmaceuticals as monoclonal antibodies and recombinant proteins represent a very important class of medicines with applications in oncology and immunodeficient diseases.
Antibody-drug conjugates (ADCs) are a class of drugs used in the treatment of different cancers. Unlike chemotherapy, ADCs are designed to only target and kill tumour cells. Structurally, ADCs are complex molecules composed of an antibody linked to a cytotoxic co
The development of liquid chromatography (LC) methods has long been done using a trial-and-error approach, also known as “one factor at a time” (OFAT). While this approach is the easiest to implement, it is both time-consuming and quite inefficient.
Traditional “absolute” methods of analysis for protein quantification include colorimetry, amino acid (AA) analysis and UV-Vis spectroscopy but each of these techniques has its limitations.
Cytokine profiling is a powerful tool to link the host immune system with disease pathogenesis and/or treatment efficacy.
