Scientific Library: results

Publication & Application note

Stress testing of Humira (adalimumab) monitored by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Arnaud Delobel

Epitope mapping of an interleukin receptor for three therapeutic antibodies by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Caroline Cajot
Arnaud Delobel

Analytical approaches for the evaluation of ADCC activity of mAbs

Authors
Arnaud Delobel
Florence Dusserre-Bresson
Eric Largy
Capucine Lepers
Cléa Mantini
Christelle Plennevaux
Fabian Vandermeers

Characterisation of the glycosylation of Humira (adalimumab) and Erbitux (Cetuximab) by high resolution mass spectrometry

Authors
Eric Largy
Fabrice Cantais
Géry Van Vyncht
Arnaud Delobel

Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Anicet Catrain,
Géry Van Vyncht

Characterisation of the glycosylation of Enbrel: Etanercept by high resolution mass spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Géry Van Vyncht

Characterisation of Humira Adalimumab by high resolution mass spectrometry

Authors
Fabrice Cantais
Anicet Catrain
Eric Largy
Géry Van Vyncht
Arnaud Delobel

Scientific poster

State-of-the art LC/MS methods applied to the characterisati on of a highly-glycosylated fusion protein: Etanercept

Authors
Eric Largy
Fabrice Cantais
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Multi-level mass spectrometric characterisation of Antibody-Drug Conjugates in a regulated environment

Authors
Eric Largy
Anicet Catrain
Arnaud Delobel
Location
Analytical Technologies Europe 2017

Development and use of 2D-LC/MS as a versatile and powerful tool for the analysis of mAbs and ADCs in a regulated environment

Authors
Eric Largy
Anicet Catrain
Géry Van Vyncht
Arnaud Delobel
Location
Analytical Technologies Europe 2016

Characterizing Deamidation and Oxidation in Adalimumab with Low pH Peptide Mapping and Middle-Up Mass Spec Analysis.

Authors
Chris Hosfield
Eric Largy
Anicet Catrain
Fabrice Cantais
Géry Van Vyncht
Michael Rosenblatt
Sergei Saveliev
Marjeta Urh
Arnaud Delobel
Location
ASMS Sanibel Conference 2016

Combination of GC, UPLC, CE and MS for the characterization of monoclonal antibody glycosylation

Authors
Arnaud Delobel
Géry Van Vyncht
Location
Bioprocess International 2010

Webinar

Mass spectrometry toolkit for the characterisation of protein glycosylation

Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each level of information you need. 

Authors
Quality Assistance
Quality Assistance webinar Fast and accurate absolute quantification of proteins and antibodies by ICP-MS

Fast and accurate absolute quantification of proteins and antibodies by ICP-MS

Although drug products issued from biotechnology have now been on the market for many years, accurate protein quantification remains a challenge.

Authors
Philippe De Raeve, Scientific Director