Scientific Library: results

Conference

TIDES Europe Damien Mouvet Oligos ICP-MS

ICP MS/MS: An innovative approach for the characterisation of therapeutic oligonucleotides

ICP-MS/MS: An Innovative Approach for the Characterisation of Therapeutic Oligonucleotides


ICP-MS/MS methodologies were developed for the characterisation of therapeutic oligonucleotides:

Authors
Damien Mouvet
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2D LC MS Proteins Quality Assistance SEP2021

Innovative 2D-LC/MS approaches for the analysis of therapeutic proteins in a regulated environment

Discover more about our applications of 2D-LC/MS at Quality Assistance and how those systems can be used in regulated environments for the characterisation of biotherapeutics.

Authors
Dr. Arnaud Delobel
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Adebiotech AATP Proteins Delobel Quality Assistance

Structural characterisation and epitope mapping by HDX-MS

Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) is an innovative tool for the characterisation of biotherapeutics.
Authors
Dr Arnaud Delobel
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Publications & Application notes

Fast and accurate absolute quantification of antibodies and antibody-drug conjugate using Isotope Dilution-Triple Quadrupole ICP-MS

Authors
Juliusz Bianga
Philippe De Raeve
Magali Perez
Arnaud Delobel
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Absolute Quantification of Oligonucleotides by ICP-MS/MS

Authors
Arnaud Delobel
Juliusz Bianga
Magali Perez
Damien Mouvet
Caroline Cajot
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Stress testing of Humira (adalimumab) monitored by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Arnaud Delobel
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Epitope mapping of an interleukin receptor for three therapeutic antibodies by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS)

Authors
Eric Largy
Caroline Cajot
Arnaud Delobel
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Analytical approaches for the evaluation of ADCC activity of mAbs

Authors
Arnaud Delobel
Florence Dusserre-Bresson
Eric Largy
Capucine Lepers
Cléa Mantini
Christelle Plennevaux
Fabian Vandermeers
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Characterisation of the glycosylation of Humira (adalimumab) and Erbitux (Cetuximab) by high resolution mass spectrometry

Authors
Eric Largy
Fabrice Cantais
Géry Van Vyncht
Arnaud Delobel
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Characterisation of Antibody-Drug Conjugates by High-Resolution Mass Spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Anicet Catrain,
Géry Van Vyncht
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Characterisation of the glycosylation of Enbrel: Etanercept by high resolution mass spectrometry

Authors
Arnaud Delobel
Eric Largy
Fabrice Cantais
Géry Van Vyncht
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Characterisation of Humira Adalimumab by high resolution mass spectrometry

Authors
Fabrice Cantais
Anicet Catrain
Eric Largy
Géry Van Vyncht
Arnaud Delobel
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Webinar

Absolute quantification of proteins: forget amino acid analysis and shift to the new gold standard

Access this 15 minutes webcast to learn more about an analytical method we have developed in our labs for the absolute quantification of proteins by ICP/MS.
Authors
Dr. Arnaud Delobel
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Mass Spectrometry protein characterisation at Quality Assistance

Access this 15 minutes webcast to learn more about our large capacity and sound expertise in Mass Spectrometry.
Authors
Dr. Arnaud Delobel
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Absolute quantification of mAbs and ADCs: forget amino acid analysis and shift to the new gold standard

Access this 45 minutes webinar to learn how ICP/MS can be used for the absolute quantification of proteins, with precision and accuracy that cannot be reached with amino acid analysis.
Authors
Dr Arnaud Delobel
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Mass spectrometry toolkit for the characterisation of protein glycosylation

Access this 45 minute webinar to learn how state-of-the-art LC/MS technologies can be implemented for the efficient study of therapeutic protein glycosylation using analyses optimised for each level of information you need. 
Authors
Quality Assistance
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Scientific poster

State-of-the art LC/MS methods applied to the characterisation of a highly-glycosylated fusion protein: Etanercept

Authors
Eric Largy
Fabrice Cantais
Arnaud Delobel
Location
Analytical Technologies Europe 2017
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Multi-level mass spectrometric characterisation of Antibody-Drug Conjugates in a regulated environment

Authors
Eric Largy
Anicet Catrain
Arnaud Delobel
Location
Analytical Technologies Europe 2017
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Development and use of 2D-LC/MS as a versatile and powerful tool for the analysis of mAbs and ADCs in a regulated environment

Authors
Eric Largy
Anicet Catrain
Géry Van Vyncht
Arnaud Delobel
Location
Analytical Technologies Europe 2016
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Characterizing Deamidation and Oxidation in Adalimumab with Low pH Peptide Mapping and Middle-Up Mass Spec Analysis.

Authors
Chris Hosfield
Eric Largy
Anicet Catrain
Fabrice Cantais
Géry Van Vyncht
Michael Rosenblatt
Sergei Saveliev
Marjeta Urh
Arnaud Delobel
Location
ASMS Sanibel Conference 2016
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