Octet

Biotherapeutics are complex molecules that require innovative techniques for accurate characterisation. Octet technology, based on Bio‑Layer Interferometry (BLI), provides fast, label‑free assays for precise concentration and kinetic measurements. It supports all stages of product development, from discovery to quality control, including characterisation, stability studies and batch‑to‑batch consistency evaluation.

ADVANTAGES OF THE EQUIPMENT

• Higher throughput with protein quantification in as little as two minutes and parallel processing of up to 96 samples
• Fast time to results thanks to automated analysis
• Real‑time analysis of binding interactions as they occur
• Crude sample compatibility
• Ease of use through a simple, integrated user interface designed for biologists

APPLICATIONS / USE CASES

Octet analyses can be developed for a wide range of biotherapeutic applications, including kinetics and affinity measurements between antibodies and their targets, Fc‑mediated effector function studies, active concentration determination, and residual concentration analysis of Protein A or Host Cell Protein.