Assessing Critical Quality Attributes of AAVs Including Aggregation and Capsid Load Using a Biozen dSEC-7 Column

By
  • Claire Butré
  • Jennifer Bouchenna
  • Damien Mouvet
  • Arnaud Delobel
  • Bryan Tackett (Phenomenex)
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In collaboration with Phenomenex, this application note demonstrates an advanced analytical approach for the characterisation of AAV Critical Quality Attributes.

By combining SEC‑MALS with the Biozen™ dSEC‑7 column, this work enables reliable assessment of aggregation, capsid content, and full‑to‑empty ratios, that are key parameters for ensuring gene therapy product quality.

This partnership showcases how integrated expertise in analytical development and separation technologies can deliver robust, high‑value insights while improving throughput and reducing sample preparation constraints.

Download the full application note to explore the methodology and results.

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